Manual of pathological anatomy . with which we are most acquaintedare the fatty, fibrous, calcareous, and waxy or amyloid. They are,except the last, of extremely frequent occurrence, but their naturehas scarcely been recognized until of late. Fatty degeneration consists in the replacement of the healthytissue of a part, by drops, or molecules of oily nature, which aredeposited, as it seems, instead of the natural material. This isthe case with the substance of the connective-tissue corpusclesshown in the figure (p. 124). This character distinguishes it fromfatty accumulation or infiltration, w
Manual of pathological anatomy . with which we are most acquaintedare the fatty, fibrous, calcareous, and waxy or amyloid. They are,except the last, of extremely frequent occurrence, but their naturehas scarcely been recognized until of late. Fatty degeneration consists in the replacement of the healthytissue of a part, by drops, or molecules of oily nature, which aredeposited, as it seems, instead of the natural material. This isthe case with the substance of the connective-tissue corpusclesshown in the figure (p. 124). This character distinguishes it fromfatty accumulation or infiltration, which may take place to a greatextent in the interstices of a tissue so as to overlay and concealits elements. In true fatty degeneration there is always destruc-tion of tissue, which does not occur when there is merely anincrease of oil in the substance of the part. A muscular fibrethus affected shows the sarcous elements, the real contractiletissue within the sarcolemma, replaced by glistening oil particles, 124 Connective-tissue corpuscles from theinner coat of an artery, in a state of fatty-degeneration. (After llindfleisch.) SO that tlie functional power of the organ is pro tanto hepatic cells in true fatty degeneration not only fill them-selves with oil, but fuse together with others, and break up into granulous films, entang-^i^- 1^- ling oil-drops; this destruction does not occur when they simplybecome loaded with oil from thepresence of a large quantity ofthis substance in the food. Theprocess by which fibrinous co-agula, or extra-vascular de-posits are broken down anddissolved, seems to be in somemeasure of the nature of fattydegeneration; there is com-monly much free oily mattervisible in the softened mass,and the exudation corpusclesseem to be thoroughly chargedwith it. Fatty degeneration isclearly a kind of atrophy, but not identical with the simple form;we have seen muscular fibres of the heart which were simplyatrophied, and had lost
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