. A treatise on mental diseases. the other cell aggregations of granula have entirely disappeared, with theexception of numerous long, narrow, chromatin rods, which prob-ably correspond to the neurosomes of Held. The cytoplasm isclear for a considerable space above the nerve hillock, showing thatthe architecture of this part of the cell is essentially different fromthat of any other portion. In the other regions of the axoneproper, according to Lugaro, Flemming, Cajal, and others, the struc-ture is fibrillary, but this is not evident in the ordinary alcoholpreparations of the mo
. A treatise on mental diseases. the other cell aggregations of granula have entirely disappeared, with theexception of numerous long, narrow, chromatin rods, which prob-ably correspond to the neurosomes of Held. The cytoplasm isclear for a considerable space above the nerve hillock, showing thatthe architecture of this part of the cell is essentially different fromthat of any other portion. In the other regions of the axoneproper, according to Lugaro, Flemming, Cajal, and others, the struc-ture is fibrillary, but this is not evident in the ordinary alcoholpreparations of the motor cell. What especial office in the cell economy do the Nissl granulasubserve ? Their pre-existence in the cell architecture may be fairlyassumed from the fact that they are demonstrable in the fresh cell 40 A TREATISE ON MENTAL DISEASES body after immersion in a fluid as little capable of inducing chemicalchanges in the protoplasm as a weak solution of methylene blue(Wright). Yan Gehuchten, Apathy, Marinesco, Cajal, Quervin,. v> h\ f- / n Fig. 8.—Normal Giant Pyramidal Cell, showing the arrangement of the Nissl axonal cone is situated at the most dependent portion of the body. After AdolfMeyer. Benda, Becker, and others, all assume their preformed function of the chromatin particles remains in doubt. Nisslplainly states that he does not know the nature of the stainablesubstance. Friedmann and Kronthal identify the Nissl body with THE FINER STRUCTURE OF THE NERVE CELL 41 the conducting substance—a manifest error, as is shown not onlyby the location of the granula, but by more positive methods thatwill be referred to later. According- to Cajal, Van Gehuchten,and Lugaro, the chromatic substance represents a reserve of nutri-ent matter for the cell; by others it is referred to as a catabolicproduct. Marinesco looks upon the chromatic substance not onlyas a nourishment reserve, but also as having a functional all this confusion of th
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