. A treatise on the nervous diseases of children : for physicians and students. lin sheaths, according tothe stage of the disease, aremore or less diseased, butthe axis-cylinders in the majority of the cases remain normal. The entireprocess may, therefore, be characterized as an interstitial inflammation, andit is owing to the preservation of the axis-cylinder that secondary degenera-tion in multiple sclerosis is a rare occurrence, indeed; although Buss hasrecorded a descending degeneration in the lumbar cord and an ascending de-generation of the columns of GoU, and of the direct cerebellar tr
. A treatise on the nervous diseases of children : for physicians and students. lin sheaths, according tothe stage of the disease, aremore or less diseased, butthe axis-cylinders in the majority of the cases remain normal. The entireprocess may, therefore, be characterized as an interstitial inflammation, andit is owing to the preservation of the axis-cylinder that secondary degenera-tion in multiple sclerosis is a rare occurrence, indeed; although Buss hasrecorded a descending degeneration in the lumbar cord and an ascending de-generation of the columns of GoU, and of the direct cerebellar tract from theeighth cervical segment into the medulla oblongata, but his observations aresurely exceptional. The absence of secondary degeneration also accountsfor the frequent absence of contractures.* * The tremor of multiple sclerosis has been attributed by some to defective isola-tion (loss of sheath) of the axis cylinders, on the supposition that the nerve currentresembles an electric current, and the axis-cylinder an electric wire ; but this is ratherfanciful Fig. 87.—Vicinity of I>ocus (Taylor.) cells ; V, DISSEMINATED SCLEROSIS. 351 Considering the importance which has been attached to the acute infec-tious diseases as an etiological factor in multiple sclerosis, it would be nat-ural to expect a very early involvement of the blood-vessels in this an involvement has been found by Ribbert and urged by Marie. Taylor,the most recent author on this subject, whom I am willing to follow in thismatter, because the autopsy in his case was on a young subject, proves thatin the earlier stages of the disease there is a distinct increase of the smallerblood-vessels and capillaries. (Fig. 87.) The specimens examined also ex-hibited small hemorrhages and migrating white blood-corpuscles. In someof the vessels there was a slight thickening of the walls and an increase inthe number of the nuclei. The perivascular spaces were dilated.
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Keywords: ., bookcentury1800, bookdecade1890, bookpublishernewyo, bookyear1895
