Manual of pathological anatomy . diseases. TUBEHCLE. The term tubercle has been applied to objects so different thatwhen the extremes are compared it will seem surprising that theyshould have ever been denoted by the same term. There are, how-ever, two principal classes of these objects, distinguished as greyand yellow tubercle. Grey Miliary Tubercle,—The former, sometimes called grey granu-lations, are about the average size of a millet-seed, but varyfrom jVn. to aio^n. in diameter,roundish, resistmg under pressure, ^^^- ^^• of a greyish, semi-transparent as-pect. The microscope shows themto
Manual of pathological anatomy . diseases. TUBEHCLE. The term tubercle has been applied to objects so different thatwhen the extremes are compared it will seem surprising that theyshould have ever been denoted by the same term. There are, how-ever, two principal classes of these objects, distinguished as greyand yellow tubercle. Grey Miliary Tubercle,—The former, sometimes called grey granu-lations, are about the average size of a millet-seed, but varyfrom jVn. to aio^n. in diameter,roundish, resistmg under pressure, ^^^- ^^• of a greyish, semi-transparent as-pect. The microscope shows themto consist of nuclei, small simplecells, and some larger cells withmany nuclei. The existence of freenuclei has been denied by somewriters, but we often find verysmall bodies in which no methodof treatment exhibits a nucleus;and which therefore seem to bonuclei themselves. The predomi- Elements from grey tubercle; nant elements are, undoubtedly, mihary granulation. small cells from about ^Vo ^^ soVoi^- i^ diameter, consisting o. 194 TUEEECLE. of a relatively large nucleus, surrounded by a small mass of proto-plasm. They sometimes approach both in size and appearancethe white cells of blood or lymph. Large polynucleated cellsof irregular shape, or mother-cells, like the myeloid cells ofbone are also often met with, but they are not constant. Theseelements are, according to some observers, imbedded in a homo-geneous basic substance; but this is, in some instances, veiyscanty, and is extremely difficult to demonstrate; according toothers, the cells are contained in an extremely fine reticulation,like that of a lymphatic gland, a kind of structure which has beencalled adenoid. We believe that sometimes a tubercle does developinto such a structure, but that in general it stops short of thisdegree of development. The arrangement of these elements in the miliary tubercle isvery curious and characteristic. The peripheral portions consist ofdistinctly formed cells, but towards the cent
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Keywords: ., bookcentury1800, bookdecade1870, booksubjectanatomy, booksubjectp
