. The endocrine organs; an introduction to the study of internal secretion . t mainly or entirely the anterior lobe, and if large is, as already mentioned, liable to affect vision and to produce headache and other symptoms of intracranial addition to the skeletal changes, others occur. The integument becomes thickened; there is increased activity of the skin glands and a tendency to an abnormal increase in the growth of the hair over the body (hypertri- chosis). Diminution of sexual activity often supervenes early in the disease, although it may be preceded by the opposite conditio
. The endocrine organs; an introduction to the study of internal secretion . t mainly or entirely the anterior lobe, and if large is, as already mentioned, liable to affect vision and to produce headache and other symptoms of intracranial addition to the skeletal changes, others occur. The integument becomes thickened; there is increased activity of the skin glands and a tendency to an abnormal increase in the growth of the hair over the body (hypertri- chosis). Diminution of sexual activity often supervenes early in the disease, although it may be preceded by the opposite condition. There is often glycosuria or simple polyuria:2 when present these conditions are probably associated wTith hypertrophy of 1 There is another kind of gigantism, without pituitary enlargement, but associatedwith defective sexual development and analogous to the increase of stature which occursas the result of castration before puberty (see Byrom Bramwell, Clinical Studies IV., Journ., June 1915). 2 Byrom Bramwell, Intracranial Tumours, 1888, and op. cit., FIG. 76.—X-ray photograph oftwo digits of an acromegalicpatient (Gushing) showingthe peculiar mushrooming ofthe ungual phalanx. Clinical Evidence regarding Functions of Pituitary 109 the pars intermedia rather than of the pars anterior. As the case advancesthey may be replaced by high degrees of sugar tolerance, due to a sub-sequent hypoplasia or degeneration ofpars intermedia. According to AndreLevi, glycosuria occurs in 30 to 50 percent, of cases of acromegaly. It is in-teresting to note that in pregnancyalso—in which the pituitary is found toundergo enlargement—glycosuria notinfrequently occurs. Marie and Marinesco were originallyinclined to the opinion that acromegalyis due to destructive disease of thegland, since in many cases it is foundpost-mortem that the tumour is ofmalignant character and that the sub-stance of the gland has been was this idea which led to the carry-ing out by v
Size: 1200px × 2082px
Photo credit: © Reading Room 2020 / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: ., bo, bookcentury1900, bookdecade1910, bookidendocrineorgansi00shar
