. The chemistry and physiology of growth. Growth; Biochemistry. 74 KARL FOLKERS During these independent researches on the nutrition of monkeys, chicks, and microorganisms, there were indications that some of the studies were concerned with a single entity, but were of unproven rela- tionship during the early work. The last few months have marked the beginning of the clarification of the chemical structural relationships between some of the factors which appear to be chemically related to folic acid. Recent papers presented at the New York Academy of Sciences and published in Science showed th
. The chemistry and physiology of growth. Growth; Biochemistry. 74 KARL FOLKERS During these independent researches on the nutrition of monkeys, chicks, and microorganisms, there were indications that some of the studies were concerned with a single entity, but were of unproven rela- tionship during the early work. The last few months have marked the beginning of the clarification of the chemical structural relationships between some of the factors which appear to be chemically related to folic acid. Recent papers presented at the New York Academy of Sciences and published in Science showed that the liver "L. casei factor" is A^ [4{( [2-amino-4-hydroxy-6-pteridyl]methyl) amino}-benzoyl] glu- tamic acid. The name pteroylglutamic acid has been suggested as a more convenient designation for this new vitamin. These elucidations of TABLE III Pteroylglutamic Acid Liver "L. casei" factor Stokstad (1943). N N /\./Xnh, \ / NHCH. ^;^^ N N OH Pteroylglutamic acid Vitamin Be Hogan and Parrott (1940) Isolation, Pfiffner and coworkers (1943). Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Parpart, Arthur Kemble, 1903-; Princeton University; Northrop, John Howard, 1891-. Princeton, Princeton Univ. Press
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