. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . *gft Fig. 321c.—Section of the embryo, main wall of the chorion and 9 times. 314 MALL. [Vol. XIX. No. 323. Pear-shaped hydatidiform mole, 120 x 90 x 65 mm. Dr. Van Williams, Baltimore. The fresh specimen was brought to the laboratory and wasfound to be composed of enlarged villi, most of which meas-ure about 5 mm. and a few fully 20 mm. in diameter. Onone end the specimen is fibrovs, from which the villi extendedinto a bloody Fig. 323.—Photograph


. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . *gft Fig. 321c.—Section of the embryo, main wall of the chorion and 9 times. 314 MALL. [Vol. XIX. No. 323. Pear-shaped hydatidiform mole, 120 x 90 x 65 mm. Dr. Van Williams, Baltimore. The fresh specimen was brought to the laboratory and wasfound to be composed of enlarged villi, most of which meas-ure about 5 mm. and a few fully 20 mm. in diameter. Onone end the specimen is fibrovs, from which the villi extendedinto a bloody Fig. 323.—Photograph of the mole. Natural size. The villi are very irregular in form, the mesoderm beinghyaline, in which there are numerous spindle-shaped of the large villi have in them a lumen which hasall of the characteristics of the ccelom; in fact, it appears asif the main wall of the chorion ramified in all directions withthe growth of the villi. One of these openings is 15 x 10 another just beside it is 7 x 2 mm. in diameter. No. i.] ORIGIN OF HUMAN MONSTERS. 315 Between the villi there are great masses of necrotic syn-cytial cells. There is more or less blood between the villi andoccasionally small masses of leucocytes may be seen. A fewof the villi are being invaded by their epithelial coverings. No. 324. Ovum, hemorrhagic and fleshy, 45 x 45 x 22 mm.; embryo,rounded and 3^ mm. long. Professor Brodel, Baltimore. The walls of the chorion are thin and fibrous and are linedby the amnion. The villi are few in number, fibrous, devoidof syncytium and imbedded


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