. Quarterly journal of experimental physiology and cognate medical sciences. ained by eosin. Occasionally there appears a vesicular-like arrangement of the cells, but this is rare. The parathyroid tissue isalways quite sharply marked off from that of the thyroid, with connectivetissue between. Effect of Administration of Thyroid and Parathj^roid,and of certain Sodium and Potassium Salts. Changes in Thyroid.—After thyroid feeding most of the vesiclesare large and distended with colloid. The epithelium cells lining them are Studies on the Endocrine (Hands H43 considerably flattened. The boundary
. Quarterly journal of experimental physiology and cognate medical sciences. ained by eosin. Occasionally there appears a vesicular-like arrangement of the cells, but this is rare. The parathyroid tissue isalways quite sharply marked off from that of the thyroid, with connectivetissue between. Effect of Administration of Thyroid and Parathj^roid,and of certain Sodium and Potassium Salts. Changes in Thyroid.—After thyroid feeding most of the vesiclesare large and distended with colloid. The epithelium cells lining them are Studies on the Endocrine (Hands H43 considerably flattened. The boundary between the colloid and protoplasmis less sharp. The cell-nuclei are deeply stained by hfetnatoxylin. Thedistention of the vehicles with colloid gives a remarkably reduced appear-ance to the intervtsicular connective tissue. The colloid is faintly stainedby eosin. Occasionally debris of cells is to be observed niinjrled with thecolloid. These chanijcs become very pronounced if the thyroid feedinjjis continued for a lonir time. But there are indivi(hial differences, and. Fio. 4.—SLction showing adjacent portions of thyroid and parathyroid of male ratfed with an addition of 2 centigr. of drj ox-pituitarj- body (posterior lobe) tothe ordinary food per diem for seven days Microphotograj)ii ; magnified 200diameters. preparation. Tile epitlielium cells lining the thyroid vesicles have a swollen appearance,and their nuclei are irregular. The colloid within the vesicles is thin ; it isstained very slightly with hsematoxylin. The parathyroid is not very ditterentin ajipearance from the normal. in some subjects all the changes which have been described are farless distinct. After the administration of sodium and potassium iodide, changes inthe appearance of the thyroid vesicles are observable which are for themost part similar to those recorded as the result of thyroid feeding. After feeding with parathyroid, there did not appear to be muchdifference betw^een the
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