. Gynecological pathology; a manual of microscopic technique and diagnosis in gynecological practice, for students and physicians. tly seen a decidedsegmentation of the nucleus, to which recently special attention hasbeen called by several authorities. There may be observed so-calledcell—, nuclear—inclusions, which are considered by some investi-gators to be protozoa. In Fig. 19 I have drawn such cells. It may beseen from this illustration how the carcinoma cells may differ in is shown still more clearly by Fig. 20, in which a cancer alveolus isseen strongly magnified. 62 CARCINO
. Gynecological pathology; a manual of microscopic technique and diagnosis in gynecological practice, for students and physicians. tly seen a decidedsegmentation of the nucleus, to which recently special attention hasbeen called by several authorities. There may be observed so-calledcell—, nuclear—inclusions, which are considered by some investi-gators to be protozoa. In Fig. 19 I have drawn such cells. It may beseen from this illustration how the carcinoma cells may differ in is shown still more clearly by Fig. 20, in which a cancer alveolus isseen strongly magnified. 62 CARCINOMA OP THE CERVIX. Here may be seen the absence of such regularity in the arrangementof the cells as is usually found in normal epithelial tissue. It may beseen that there is a confusion of large, larger, and smaller cells, betweenwhich are a few capillaries, a condition not occurring in normal epithe-lium. It is also noticeable that the cells do not always lie side by side, asin Fig. 20, but that very often leucocytes are found between these cells(Fig. 21). After this description, we may define carcinoma as follows: Car-. Figuke 20.—Cancek Alveolus bi* High-power Lens (fixed in bichloride). + a, mononuclear cells ; 6, very large cells with bubble-like cell contents; c, capillaryfilled with blood. cinoma is a neoplasm which consists of a tissue groundwork, more orless rich in cells, in which groups of various large epithelial cells arelodged. The latter form cords and penetrate the tissue, which theyenter irregularly and in every direction. These cords are sometimesformed of a few cells, and sometimes of large masses. They breakthrough other tissue layers and tissue forms, whose boundaries are de-stroyed by the epithelial cells entering them. They increase in this wayuntil finally nothing is left of the original tissues. A carcinoma finds nolimit at the muscular layer, breaks through the vessel walls, and de- CARCINOMA OF THE CERVIX. 63 stroys the gland boundaries; in a wo
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