. The development of the human body : a manual of human embryology. Embryology; Embryo, Non-Mammalian. 22 OVULATION AND THE CORPUS LUTEUM prominence, only an exceedingly thin membrane separating the cavity of the follicle from the abdominal cavity. This thin mem- brane finally ruptures, and the liquor folliculi, which is apparently under some pressure while contained within the follicle, rushes out through the rupture, carrying with it the ovum surrounded by some of the cells of the discus proligerus. The immediate cause of the bursting of the follicle is not yet clearly understood. It has bee


. The development of the human body : a manual of human embryology. Embryology; Embryo, Non-Mammalian. 22 OVULATION AND THE CORPUS LUTEUM prominence, only an exceedingly thin membrane separating the cavity of the follicle from the abdominal cavity. This thin mem- brane finally ruptures, and the liquor folliculi, which is apparently under some pressure while contained within the follicle, rushes out through the rupture, carrying with it the ovum surrounded by some of the cells of the discus proligerus. The immediate cause of the bursting of the follicle is not yet clearly understood. It has been suggested that a gradual increase of the liquor folliculi under pressure must in itself finally lead to a rupture, and it has also been pointed out that just before the matura- tion of the follicle the theca interna undergoes an exceedingly rapid development and vascularization which may play an important part in the phenomenon. Normally the ovum when expelled from its follicle is received at once into the Fallopian tube, and so makes its way to the uterus, in whose cavity it undergoes its de- velopment. Occasionally, how- ever, this normal course may be interfered with, the ovum coming to rest in the tube and there undergoing its development and producing a tubal pregnancy; or, again, the ovum may not find its way into the Fallopian tube, but may fall from the follicle into the abdominal cavity, where, if it has been fertilized, it will undergo development, producing an abdominal preg- nancy; and, finally, and still more rarely, the ovum may not be expelled when the Graafian follicle ruptures and yet may be fertilized and undergo its development within the follicle, bringing about what is termed an ovarian pregnancy. All these varieties of extra-uterine pregnancy are, of course, exceedingly serious, since in none of them is the fetus Fig. 12.—Ovary of a Woman Nine- teen Years of Age, Eight Days after Menstruation. d, Blood-clot; /, Graaffian follicle; th, theca.


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