Report of first expedition to South America, 1913 . les Rocha-Lima observed in the degenerating cells were parasites isgiven. It seems remarkable that he should draw such sweep-ing conclusions regarding the etiology of this disease from thestudy of one case observed late in the course of the disease. Finally Cole ^ studied histologically the lesions of a case ofverruga observed in Jadassohns clinic in Berne, and alsothose produced in monkeys by inoculation with verrugamaterial. He concludes that ^as the other granulomata —tuberculosis, syphilis, sporotrichosis, actinomycosis, etc., havetheir o


Report of first expedition to South America, 1913 . les Rocha-Lima observed in the degenerating cells were parasites isgiven. It seems remarkable that he should draw such sweep-ing conclusions regarding the etiology of this disease from thestudy of one case observed late in the course of the disease. Finally Cole ^ studied histologically the lesions of a case ofverruga observed in Jadassohns clinic in Berne, and alsothose produced in monkeys by inoculation with verrugamaterial. He concludes that ^as the other granulomata —tuberculosis, syphilis, sporotrichosis, actinomycosis, etc., havetheir own significant histological changes, so also does verrugaperuviana, belonging to the same class, have its own character-istic microscopical picture. It is characterized by a dilatationof the lymph vessels and a choking of their lumina with mono-and polymorphonuclear leucocytes; also by an infiltrationaround these vessels of plasma cells, fibroblasts, mononuclear 1 Cole: Arch, internal rned., 1912, x, 668. J. Cutan. Dis., N., Y., 1913, xxxi, \- 3^


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