. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. I MV j* | fH f fttj|l '((""([j. SEC il'Li { ..._ 1MI ifcHr (! FIGURE 4. Changes in the pattern of electrical activity in the isolated ganglion resulting from 5-HT treatment. The upper trace is a representative burst before drug treatment, the lower trace a representative burst after bathing the ganglion for one minute in 1 X 10"* M 5-HT. five-minute stimulation intervals, drug-free saline was perfused. During the next two five-minute intervals 100 ml. of BOL were perfused and during the last six f


. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. I MV j* | fH f fttj|l '((""([j. SEC il'Li { ..._ 1MI ifcHr (! FIGURE 4. Changes in the pattern of electrical activity in the isolated ganglion resulting from 5-HT treatment. The upper trace is a representative burst before drug treatment, the lower trace a representative burst after bathing the ganglion for one minute in 1 X 10"* M 5-HT. five-minute stimulation intervals, drug-free saline was perfused. During the next two five-minute intervals 100 ml. of BOL were perfused and during the last six five-minute intervals drug-free saline was again perfused. BOL ( X 10'5 M) alone causes a slight increase in heart rate, the mean rate for 15 different hearts being beats per minute before BOL treatment and beats per minute after BOL treatment. The relative rate for each of the 13 stimulation periods was computed by taking the ratio of the rate during the stim- ulation period to the rate just previous to that same stimulation period. BOL is an effective antagonist of inhibitor nerve action in the Limulus heart. The mean relative rate during stimulation of the inhibitor nerves for each of the 13 stimulation periods is shown in Figure 5. Stimulation of the inhibitor nerves before BOL treatment resulted in a mean decrease in rate of beats per minute. The relative rate was (SD = ), , stimulation reduced the rate by 72%. After BOL treatment the decrease in rate was beats per minute and the relative rate was (SD = ), , stimulation reduced the rate by only 34%.. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Marine Biological Laboratory (Woods Hole, Mass. ); Marine Biological Laboratory (Woods Hole, Mass. ). Annual report 1907/08-1952; Lillie, Frank Rattray, 1870-194


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Keywords: ., bookauthorlilliefrankrat, booksubjectbiology, booksubjectzoology