Illustration of a fibroblast growth factor receptor (FGFR) dimer in a cell membrane. An FGFR inhibitor molecule (yellow) is bound to the receptor. The human fibroblast growth factor receptor family (FGFR1-4) regulates important biological processes including embryogenesis, angiogenesis (blood vessel formation), tissue homeostasis, and cell proliferation. Mutations in FGFRs that lead to constant activation of FGFR and its downstream signalling pathways are involved in a number of cancers.

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Photo credit: © HYBRID MEDICAL ANIMATION/SCIENCE PHOTO LIBRARY / Alamy / Afripics
License: Licensed
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