Organic and functional nervous diseases; a text-book of neurology . quent thrombosis of thefiner vessels of the cord is the method by which the disease attacks thisorgan. The form of disease described by Erb as syphilitic spasticparalysis has been found to be a chronic myelomalacia of the lowerdorsal region due to endarteritis with secondary degeneration.^ Insome forms of poisoning, notably by lead, mercury, phosphorus, and Lancet, October, 1902. MYELITIS. 397 occasionally alcohol, disseminated foci of myelitis have been discovered,as well as multiple neuritis, and this has led to the supposit
Organic and functional nervous diseases; a text-book of neurology . quent thrombosis of thefiner vessels of the cord is the method by which the disease attacks thisorgan. The form of disease described by Erb as syphilitic spasticparalysis has been found to be a chronic myelomalacia of the lowerdorsal region due to endarteritis with secondary degeneration.^ Insome forms of poisoning, notably by lead, mercury, phosphorus, and Lancet, October, 1902. MYELITIS. 397 occasionally alcohol, disseminated foci of myelitis have been discovered,as well as multiple neuritis, and this has led to the supposition thatthe cord may be directly affected by toxins and toxic agents. Thatcertain agents have a selective action upon the spinal cord is evidentfrom our knowledge of the action of strychnine, which excites its activity,and of the coal-tar products and bromide and chloral, which diminishits activity. It is not impossible that the general feebleness and tremoroccasionally seen in chronic bromide poisoning is due to defective nutri-tion of the spinal cord. Fig. Acute tranverse myelitis in dorsal region, due to the presence of bacillus coli and white columns are infiltrated and in a state of acute Inflammation. (Marincsco, InternationalMedical Congress, Paris, 1900.) Males are affected more frequently than females by acute myelitisand by myelomalacia. This is because they are more commonlyexposed to the usual causes of the affection. While no age is exempt,the majority of the cases occur between the ages of twenty-five andforty-five years. Pathology. — The pathological changes in acute myelitis have beenbest described by Mari nesco.^ The location of the lesion may be limitedto one or two segments of the cord, under which circumstances one ofthe symptomatic types of transverse myelitis is produced, or the lesionmay be disseminated through the various segments of the cord, normaltissue intervening between the inflammatory foci, when the clinicalaspect is that
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