. A manual of clinical diagnosis by means of microscopical and chemical methods, for students, hospital physicians, and practitioners . bauer and Vogels UrinaryAnalysis (ninth edition) it is stated that as to the significanceof tube-casts, it must be remembered that these, according 1<» <»nrpresent knowledge, consist of albumin, which coagulates under theinfluence of the acid reaction of the urine, in the renal paren-chyma, in a peculiar hyaline manner. They represent merely a 1 Martini, f. klin. Chir., 1884, vol. xvi. p. 157. v. Jaksch, Deutech. , 1888, vol. xiii. Xs. 40
. A manual of clinical diagnosis by means of microscopical and chemical methods, for students, hospital physicians, and practitioners . bauer and Vogels UrinaryAnalysis (ninth edition) it is stated that as to the significanceof tube-casts, it must be remembered that these, according 1<» <»nrpresent knowledge, consist of albumin, which coagulates under theinfluence of the acid reaction of the urine, in the renal paren-chyma, in a peculiar hyaline manner. They represent merely a 1 Martini, f. klin. Chir., 1884, vol. xvi. p. 157. v. Jaksch, Deutech. , 1888, vol. xiii. Xs. 40and II. 3 Bizzozero, loc. eit. Thomas. Arch. f. Heilk., W. vol. si. p. 130. Pollaku. T6rok, Arch. f. exper. Path. u. vol. xxv. p. -7. 532 THE URINE. solidified portion of the albumin held in solution by the urine ; theirelimination essentially indicates the existence of an recently, however, it has been suggested, that tube-casts arethe product of a faulty metamorphosis^ or of inflammatory irrita-tion of the renal epithelium, and that a secretion from these cells or Fig. ^<3/ a and b, Cylindroids from the urine incongested kidney, v. Jaksch.) Fig. 126. / A Mucous cylinders. a disintegration of their protoplasm occurs, which results in theformation of cylindroids or true Clinical Significance of Tube-casts.—Formerly the occurrence oftube-casts in urine was held to indicate the existence of nephritis. 1 See also Rindfleisch. Lehrbuch d. path. Gewebelehre, Leipzig, 1875, p. Virchows Arehiv. 1ST9. vol. lxxvi. p. 85. Eovida. loc. cit. Kobler. Ribbert. Centralbl. f. d. med. Wiss., 1880, vol. six. p. 305. MICROSCOPICAL EXAMINATION OF THE UBINR 533 This view has been abandoned, however, for the same reasons whichled to the rejection of the theory that albuminuria invariably indi-cates Bright^ disease (see above). The statement is frequently made in text-books thai tube-castsmay occur in the urine of perfec
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