A text-book of pharmacology and therapeutics; or, The action of drugs in health and disease, . Tiarint-s i^f auricle (upper) and \entriele (lower)in tliird stage of digitalis action. Auricle and ven-tricle each beating regularly but at different levers move do\vii\var<] in sj^stolc, upward indiastole. THE DIGITALIS SERIES 40<. proviso that the diminished conduction in the latter is of muscularorigin, while in the mammals it is inhibitory in character. The heartin mammals is generally found in the position of diastole in cases offatal digitalis poisoning, and this has been suppo
A text-book of pharmacology and therapeutics; or, The action of drugs in health and disease, . Tiarint-s i^f auricle (upper) and \entriele (lower)in tliird stage of digitalis action. Auricle and ven-tricle each beating regularly but at different levers move do\vii\var<] in sj^stolc, upward indiastole. THE DIGITALIS SERIES 40<. proviso that the diminished conduction in the latter is of muscularorigin, while in the mammals it is inhibitory in character. The heartin mammals is generally found in the position of diastole in cases offatal digitalis poisoning, and this has been supposed to indicate afundamental tlifference in the action of digitalis on the amphibianand mammalian heart. The dilatation is not, however, a direct resultof the digitalis, but isprobably induced by the Fig. 51 poisons formed in the heart -. , . . i . , by its own activity. Whenthe mammalian heart isexcised, and blood contain-ing digitalis is perfusedthrough the coronary ves-sels, complete systolic stand-still of the ventricle resem-bling that seen in the frog-is often the final both frog and mammalthe increase in activity isattended by an augmentedmetabolism in the heart. Vessels.—Small quantitiesof digitalis and its allies, suchas are used in medicine, haveno direct action on the blood-vessels, but larger amounts induc
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Keywords: ., bookcentury1900, bookdecade1910, booksubjecttherapeutics, bookyea
