. Diseases of bones and joints . es,viz., their painlessness, and the apparent inadequacyof their cause. Tabetic Osteoarthropathy may occur in any stageof tabes, preataxic or late. Sometimes it is seenyears before the onset of other symptoms. It ismore frequent in men than in women in about thesame ratio as the causal disease, and is seen muchmore often in the lower than in the upper reverse is true of the lesions in syringomyelia. MORBID ANATOMY. The pathology of Charcots joint is somewhat asfollows: A low grade inflammation takes place in Marrowthe marrow of one of the articula
. Diseases of bones and joints . es,viz., their painlessness, and the apparent inadequacyof their cause. Tabetic Osteoarthropathy may occur in any stageof tabes, preataxic or late. Sometimes it is seenyears before the onset of other symptoms. It ismore frequent in men than in women in about thesame ratio as the causal disease, and is seen muchmore often in the lower than in the upper reverse is true of the lesions in syringomyelia. MORBID ANATOMY. The pathology of Charcots joint is somewhat asfollows: A low grade inflammation takes place in Marrowthe marrow of one of the articulating bones, which Changes thegradually eats away the bone trabeculae. This in- Most strikir|gflammation is not general but seems to occur in cer-tain areas. In other places the marrow is largelyfatty. In time the cartilage is destroyed, the in-flammatory process has access to the joint, and the 152 DISEASES OF BONES AND JOINTS synovia also becomes involved. The joint now be-comes filled with fluid. The bone is killed in larger o. Fig. 63. Low power photomicrograph of peculiar focus found at thejoint surface of the bone in a Charcots knee. It was composedlargely of fibrous tissue, continuous with that covering the headof the bone. Indications of new bone formation can be seen atB. Portions of the enclosing bony wall of this focus werethickened. Bone trabeculae may be seen on the left of the pic-ture, and bone and marrow indistinctly below. C, collection ofround cells. and smaller pieces, which are thrown out into thejoint cavity, and occasion the creaking and DISEASES OF BONES AND JOINTS 153 crumbling so characteristic of this disease. Thereis apparently some effort at repair of the damageby nature at the spot where it has occurred, butthe effort is ineffectual. Natures efforts at re-pair are largely confined to producing a compen-
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Keywords: ., bookcentury1900, bookdecade1910, booksubjectbon, booksubjectbones
