. American journal of physiology. Figure 1. — Perfu-sion arrangement. Perfusion Experiments on Excised Kidneys. 249 of 5 cm. in the level of the reservoir, even when the vein was pressure in the oncometer was usually kept between 15 cm. and 30cm. of water. Other modifications of the apparatus will be described in connectionwith the experiments. Before drawing any conclusions, the numerical results were alwaysplotted as curves. E. Phenomena occurring during Perfusion with SodiumChloride Solutions under Constant Conditions. In the course of a prolonged perfusion with sodium chloride sol
. American journal of physiology. Figure 1. — Perfu-sion arrangement. Perfusion Experiments on Excised Kidneys. 249 of 5 cm. in the level of the reservoir, even when the vein was pressure in the oncometer was usually kept between 15 cm. and 30cm. of water. Other modifications of the apparatus will be described in connectionwith the experiments. Before drawing any conclusions, the numerical results were alwaysplotted as curves. E. Phenomena occurring during Perfusion with SodiumChloride Solutions under Constant Conditions. In the course of a prolonged perfusion with sodium chloride solu-tion, the vein and ureter flow undergo certain changes which may bedivided into four stages. These are seen with tolerable uniformity inalmost every suitable First Second Stage Third Figure 2. — The heavy line indicates the vein-flow, the light linethe ureter flow during prolonged perfusion. The first stage, following immediately on establishing the perfusion,consists in a rapid rise of the vein and ureter flow and of theoncometer. The vein flow usually reaches its maximum within fifteenminutes, but in rare cases this may not occur until thirty ureter flow continues to increase for a much longer time. Theperiod at which the oncometer reaches its maximum is variable. The second stage is characterized by a diminution of the vein flowand a continued increase of the ureter flow. It begins about fifteenminutes after starting the perfusion and continues from one and one-half to two and one-half hours. The behavior of the oncometer issomewhat variable. In the third stage, the curves for the vein and ureter flow are prac-tically parallel and horizontal, with a slight tendency to fall. Itbegins in one and one-half to two a
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