Science . d pathological laboratories themethod is extremely useful. It has, more-over, been found of very practical value inmedical pathological laboratories, where it isused in rapid histological work. Perhaps the greatest general good could bederived from its use in high schools, normalschools and smaller colleges, for which theapparatus for the paraffine method is too ex-pensive, where the time is insufficient, and thacourses necessarily too elementary to includethe study of the paraffine method. It isespecially to workers in these institutions thatI wish to direct attention to this freezi
Science . d pathological laboratories themethod is extremely useful. It has, more-over, been found of very practical value inmedical pathological laboratories, where it isused in rapid histological work. Perhaps the greatest general good could bederived from its use in high schools, normalschools and smaller colleges, for which theapparatus for the paraffine method is too ex-pensive, where the time is insufficient, and thacourses necessarily too elementary to includethe study of the paraffine method. It isespecially to workers in these institutions thatI wish to direct attention to this freezingmicrotome technique. The method shouldprove of immense value in such institutionson account of its cheapness, speed and generalusefulness. Hundreds of excellent sectionscan be cut in a very short time and theapparatus is always ready for use. An effi-cient apparatus such as that shown in thefigure, can be obtained for $16 (duty free).It is sold by J. Swift & Son, No. 81 Totten-ham Court Road, The apparatus is shown in the accompany-ing figure. The material to be cut is firstplaced in a ten per cent, gum-arabic may be soaked in this for one to twenty-four hours, according to the size of the ma-terial. It can, when necessary, be kept in thegum arable for only a few minutes or even afew seconds, though the longer soaking will May 10, 1907] SCIENCE 749 give a better infiltration. It is then orientedin a drop of ten-per-cent. gum arabic placedon the small brass plate (a) in the center ofthe table, and a spray of ether is atomizedagainst the corrugated under surface of thisplate, producing the necessary low temi)era-ture. The atomizer is usually worked byhand with a double bulb, but I have found acompressed-air tank (such as physicians use)a very great convenience, as such a tankallows of the unhindered use of both handsin the microtome work. It also admits ofmore rapid freezing. I have been able withthis apparatus to freeze material in eightseconds on a warm s
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