Surgery; its theory and practice . emedies as are appropriate for scurvy. MoLLiTiES ossiuM or OsTEO-MALACiA is a rare disease, character-ized by softening of the bones through the re-absorption of theirearthy salts and destruction of their osseous lamellse. Cause.—It is a of adult life, and most often occurs infemales during the child-bearing period. Sometimes it appearsto be hereditary ; but its causation is practically unknown. rath»/oi,y.—The disease appears to begin in the medullarytissue of bone, which is replaced by a soft, dark-red gelatinousmaterial somewhat resembling spleen-
Surgery; its theory and practice . emedies as are appropriate for scurvy. MoLLiTiES ossiuM or OsTEO-MALACiA is a rare disease, character-ized by softening of the bones through the re-absorption of theirearthy salts and destruction of their osseous lamellse. Cause.—It is a of adult life, and most often occurs infemales during the child-bearing period. Sometimes it appearsto be hereditary ; but its causation is practically unknown. rath»/oi,y.—The disease appears to begin in the medullarytissue of bone, which is replaced by a soft, dark-red gelatinousmaterial somewhat resembling spleen-pulp, whilst later the wholebone, with the exce])tion of a thin layer immediately beneath theperiosteum, becomes replaced by this material and reduced tolittle more than a mere shell, ihe bone appears first to becomedecalcified and then destroyed. The exact pathology of the pro-cess is not known, but it has been suggested that the decalcification of the bone is due to the action of lactic acid, which has MOLLITIES OSSIUM. 229. IMicroscopical appearance of a fragment ofbone in mollifies ossium. (From been found both in the bone and the urine, or to excess of car-bonic acid in the veins of the medulla, which are said in the earlystages to be enlarged. The microscopical appearances lend somesupport to this view, as in abone-trabecula (see Fig. 72) the P°- 7^- decalcification is seen to beginaround the Haversian canals andmedullary spaces, the bone-corpuscles in these parts havingentirely disappeared, while in thecentre of the trabecula they arestill present. At times the gela-tinous material is in places yellowand fatty-looking. In some ofthe specimens in St. Bartholo-mews Hospital the medullaappears entirely filled with fatty material; but it is a question whether these specimens, thoughcalled mollities ossium, are not of a different nature from the dis-ease to which the term is generally applied, and do not ratherdepend upon a senile change. Symptoms.—In t
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Keywords: ., bookcentury1800, bookdecade1890, booksubjectsurgery, bookyear1896
