Human physiology . heory of internal secretion, starting from the fact thatafter ligation of the ducts or internal pancreatic lobes in therabbit, the islets were left unaltered, while the alveoli weremodified and disappeared, without causing any true diabetes. The same fact had been described by Vassale ten years earlier,but not with the intention of localising the internal secretionin the islets: he merely sought to contradict Lewaschew, whoaffirmed the unitary character of the two pancreatic tissues. Mankowski and Lombroso failed to confirm the results ofSchultze and Ssobolew. They found tha
Human physiology . heory of internal secretion, starting from the fact thatafter ligation of the ducts or internal pancreatic lobes in therabbit, the islets were left unaltered, while the alveoli weremodified and disappeared, without causing any true diabetes. The same fact had been described by Vassale ten years earlier,but not with the intention of localising the internal secretionin the islets: he merely sought to contradict Lewaschew, whoaffirmed the unitary character of the two pancreatic tissues. Mankowski and Lombroso failed to confirm the results ofSchultze and Ssobolew. They found that ligation of the ducts inthe rabbit produced alterations not merely in the alveoli butalso in the islets, which diminished in size and number. Many other authors (Tiberti, Pende, Marassini, etc.) obtainedsubstantially the same results; some (Laguesse, Marassini),however, argued from the greater resistance of islets as comparedwith alveoli, that the absence of glycosuria must be referred to the 104 PHYSIOLOGY ~~~ ~~~ ^N b -—-_^~ v1 survival of the islets, the internal secretion being served by the islots only. Lornbroso objected that the necessary counterproof was wanting. It is not known whether complete extirpation of the pancreas (as far as possible) wouldproduce glycosuria in the is known, indeed, that completeablation of the pancreas is not followedby glycosuria in all animals. It isabsent in many granivorous birds(pigeons), while it is seen in caruivora(crows, falcons). Moreover, the effectsof total excision of an organ, and ofthe slow and gradual suppression ofits function, may differ in the dog, according to Hedon,glycosuria may be absent or very slightwhen a pancreas previously altered byinjection of paraffin into its ducts isexcised. After tying or cutting the ducts,and after transplanting a segment ofthe pancreas in the dog, numerousobservers (Hedon, Moruet, Laguesse,Ssobolew, De Dominicis, Hansemann,Lombroso) found that conspicuo
Size: 1482px × 1687px
Photo credit: © The Reading Room / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: ., bookcentury1900, bookdecade1910, booksubjectphysiology, bookyear1
