. Archives of physical medicine and rehabilitation . arenearly all destroyed, that is when cellproliferation is checked and only latentcancer cells are removed. In manycases at least imbedding radium takesthe place of operation, but until wehave more data, it may be advisableto operate between four and six weeksafter primary radiation, when cancercells are sickened, as William J. Mayoexpresses it. In late cases radiation as just described is superior to any formof an operation primarily, and in thesecases if the breast is removed, at leastthe axilla should scarcely, if ever, beopened following


. Archives of physical medicine and rehabilitation . arenearly all destroyed, that is when cellproliferation is checked and only latentcancer cells are removed. In manycases at least imbedding radium takesthe place of operation, but until wehave more data, it may be advisableto operate between four and six weeksafter primary radiation, when cancercells are sickened, as William J. Mayoexpresses it. In late cases radiation as just described is superior to any formof an operation primarily, and in thesecases if the breast is removed, at leastthe axilla should scarcely, if ever, beopened following radiation. At pres-ent probably the safest method to fol-low is to give sufficient surface treat-ment of radium or x-ray and then twoor three weeks later to imbed radiumthroughout the breast, into the glandsof the axilla and into the glands lead-ing from the axilla to the breast, andthen four weeks later to removethe breast and as much of the adjacent —Read at the Annual Meeting ofThe Radiological Society of NorthAmerica, Chicago, Dec. 7, Figuve T—Inoj)erable carcinoma ofthe toreast, thirty-seven needles in-serted into the hreast and adjacenttissues for five liours, two monthsafter surface application of x-rayand radium had been given. rigfure II.—Roentifenogram of the same case, showing the needles imbeddedin the tissues. 317 UADIUM IN THKATMENT OK tissue as is dfemcd nfcfssary. If lli<-removal is done .it this lime, it will In-done before much fibrous tissue In all the progress made m recentyears in radiotherapy, nothmg has beenevolved of such significant import in thetredtmeni of carcinoma of the breast,as the advanced method of imbeddingradium, with its manifold and variedadvantages and possibilities in deeptherapy. By imbedding radium throughout the entire breast, in the ax-illa, into the glands leading from thebreast to the axilla and into the glandsbelow the clavicle, this supplemented bydeep x-ray therapy, radiation is madi-as thorough as a


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