. The pathology and treatment of diseases of the ovaries. abundant pro-toplasm. The inner layer is muchthicker, and formed of large massesof rounded cells, and the two layersare connected by numerous trabe-culse, the stroma between whicheventually gives rise to the connec-tive-tissue capsule, or tunica albugi-nea of the adult ovary. Subsequently in the course of de-velopment the germinal epitheliumbecomes still more thickened to .38mm., and becomes marked into threedistinct layers (Fig. 9, g, e). Theseconsist of an outer epithelial layer,having an average thickness of .03mm.; a middle layer of


. The pathology and treatment of diseases of the ovaries. abundant pro-toplasm. The inner layer is muchthicker, and formed of large massesof rounded cells, and the two layersare connected by numerous trabe-culse, the stroma between whicheventually gives rise to the connec-tive-tissue capsule, or tunica albugi-nea of the adult ovary. Subsequently in the course of de-velopment the germinal epitheliumbecomes still more thickened to .38mm., and becomes marked into threedistinct layers (Fig. 9, g, e). Theseconsist of an outer epithelial layer,having an average thickness of .03mm.; a middle layer of small nests,about . 1 mm. in thickness ; and aninner layer of larger nests, whichhas an average thickness of .23 these three layers the epitheliumhas undergone important modifica-tions. The greater part of the gran-ular contents of the nuclei of thecells has become clear, the otherpart remaining as a mass taking thecolor of staining materials verydarkly, and somewhat later takinga stellate figure, these two forms being spoken of as the granular2. Fig. 9 (after Balfour).—g, e. germina!epithelium in three layers; A, hilum, withcanals, c c. 18 DISEASES OF THE OVAEIES. and stellate stages of the nucleus. Still later the nuclear massforms a beautiful reticulation, as seen in the spores of the algse. As already said, some of the cells enlarge, and are recognizedas the primitive ova, and these are now increased in of the cells again diminish in size, becoming of an ovalform, the nucleus retaining its primitive character, and notgoing through the changes above described. The cells subse-quently form the epithelium of the Graafian follicle. They maybe seen arranging themselves around the primitive ova justformed. At the hilum of the ovary the tubules (c, c, Fig. 9)have by this time almost disappeared. As the ovary grows, the outermost layer of the epithelialelements becomes more and more separated by the fusiform-cellstroma, and the nests of the middle layer becom


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Keywords: ., bookcentury1800, bookdecade1880, booksubjectovarian, bookyear1883