. Biology of the laboratory mouse. Mice as laboratory animals; Mice; Animals, Laboratory; Mice. I go BIOLOGY OF THE LABORATORY MOUSE tumor shows a central amorphous mass which grades over into desquamated stratified squamous epithehum. This in turn grades over into definite adenocarcinoma. This can be considered as adeno-acanthoma, but a more probable explanation is that metaplasia has occurred changing glandular epithelial cells into stratified squamous epithelium (Fig. loiA). These two characteristics in their most extreme manifestations could be considered as special types of breast cancer.
. Biology of the laboratory mouse. Mice as laboratory animals; Mice; Animals, Laboratory; Mice. I go BIOLOGY OF THE LABORATORY MOUSE tumor shows a central amorphous mass which grades over into desquamated stratified squamous epithehum. This in turn grades over into definite adenocarcinoma. This can be considered as adeno-acanthoma, but a more probable explanation is that metaplasia has occurred changing glandular epithelial cells into stratified squamous epithelium (Fig. loiA). These two characteristics in their most extreme manifestations could be considered as special types of breast cancer. However, an interpretation of. Fig. loi.—Two features frequently observed in adenocarcinoma of the mammary gland. A, metaplasia of the glandular epithelium in a nest of tumor cells (center of figure) to keratinized squamous epithelium (X200); B, cystic blood-filled spaces sur- rounded by the tumor cells of adenocarcinoma (X200). the histological picture presented by the various forms assumed by adenocarcinoma of the mammary gland probably does not require these subdivisions. Carcinoma Simplex of the Mammary Glands Histologically this tumor is so undifferentiated that its appearance is frequently difficult to associate with that of the mammary gland from which it originated (Fig. 102). However, one can find small foci and traces of adenocarcinoma that blend with the carcinoma simplex cells forming the bulk of the tumor mass. The architecture of the tumor shows compact masses of epithelial tumor cells growing in long, broad, branching and anastomosing bands or in a com-. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Roscoe B. Jackson Memorial Laboratory; Little, Clarence C. (Clarence Cook), b. 1888; Snell, George D. (George Davis), 1903-; Dingle, John H. (John Holmes), 1908-. Philadelphia, The Blakiston c
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