. Annals of surgery . MULTIPLE MYELOMA OF THE PLASMA-CELL TYPE round nuclei was somewhat condensed at the periphery, but coarse, irregular, chro-matic clumps were scattered through the nuclear body. A few cells containedtwo nuclei. The cellular cytoplasm was slightly cloudy but almost smooth andgenerally basophilic; with methylene blue-eosin and with Giemsa stain, many cellswere shown to possess neutrophilic and a few. eosinophilic cytoplasm. In short,the tumor elements somewhat resembled plasma cells. There were, however,certain differences. None of the tumor cells had the pale perinuclear ha
. Annals of surgery . MULTIPLE MYELOMA OF THE PLASMA-CELL TYPE round nuclei was somewhat condensed at the periphery, but coarse, irregular, chro-matic clumps were scattered through the nuclear body. A few cells containedtwo nuclei. The cellular cytoplasm was slightly cloudy but almost smooth andgenerally basophilic; with methylene blue-eosin and with Giemsa stain, many cellswere shown to possess neutrophilic and a few. eosinophilic cytoplasm. In short,the tumor elements somewhat resembled plasma cells. There were, however,certain differences. None of the tumor cells had the pale perinuclear halo socharacteristic of plasma cells, nor did they give typical staining reactions. Scattered between these plasma cell-like elements there were moderate num-bers of small round cells about the size of lymphocytes, possessing a compact deep-staining nucleus and very little basophilic cytoplasm. Occasionally a field wasencountered with two or three huge, irregular-shaped elements, which closelyresembled megalokaryoc>
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Keywords: ., bookcentury1800, bookdecade1880, booksubjectsurgery, bookyear1885
