A treatise on the nervous diseases of children, for physicians and students . sclerosis which they consider to be the cause of epilepsy-such sclerosis starting from a focus of disease. Van Gieson has made a very valuable contribution to this subject by a study of corticalamoved by McBurney,cases of Starr. Vandemonstrates most sat-(faffliWltj/ islactorily the changes in the^^ffifiA lar»e pyramidal cells of the cor-tex and in the neuroglia. Hefinds that the ganglion cellsare affected by a series of de-generative changes, which intheir most advanced stages re-sult in an almost complete dis-fig. 3
A treatise on the nervous diseases of children, for physicians and students . sclerosis which they consider to be the cause of epilepsy-such sclerosis starting from a focus of disease. Van Gieson has made a very valuable contribution to this subject by a study of corticalamoved by McBurney,cases of Starr. Vandemonstrates most sat-(faffliWltj/ islactorily the changes in the^^ffifiA lar»e pyramidal cells of the cor-tex and in the neuroglia. Hefinds that the ganglion cellsare affected by a series of de-generative changes, which intheir most advanced stages re-sult in an almost complete dis-fig. 39.—Diffuse Neuroglia Sclerosis solution of the cell, and yet thisof the cortex in Epilepsy (after degeneration is not extensive Chaslin). ° , . , ,, ,, enough to involve the cells souniversally as to interfere with their topographical distri-bution. Some of the degenerative changes of the cells will beevident in the figure below taken from Van Giesons article. There is a decided change—a true hyperplasia—in the mm m. Fig. 40.—Various Phases of the Earlier Stages of the Degeneration of the GanglionCells. The thin lines enclosing the cells w and u represent the pericellular spaces;the cells x and y show the earliest stages, w and s later stages, and k shows theultimate destruction of the whole of the ganglion-cell body, leaving nothing but thenucleus lying in an empty space. (Van Gieson.) EPILEPSY. 77 neuroglia tissue ; clusters of an increased number of veryyoung and seemingly proliferating neuroglia cells are vis-ible in the vicinity of the small pyramids. These findings were very much the same in two cases :in one the condition was due to a foreign body, and in theother an old cicatrix seems to have induced a similar path-ological state in the neighboring tissue. To appreciatesuch researches at their true worth, it is important to notethat they have reference to the early conditions only. Whatthe nature of the secondary changes is, and how these are nm§mum iiiifi ii
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Keywords: ., bookcentury1800, bookdecade1890, booksubjectnervous, bookyear1895
