. Electronic apparatus for biological research. Electronic apparatus and appliances; Biology -- Research. (a) (b) Figure Graphical correction for time constant distortion at all parts of the curve: if the value of the subtangent be found for an experimental arrangement, it can then be used to correct for distortion in a recording. In Figure the response to a voltage step is given by the exponential curve BCD, and the level which it will finally attain is AD. At any point C, the value CF is less than the full response FE by an amount CE. If the tangent at C be drawn to cut AD, then
. Electronic apparatus for biological research. Electronic apparatus and appliances; Biology -- Research. (a) (b) Figure Graphical correction for time constant distortion at all parts of the curve: if the value of the subtangent be found for an experimental arrangement, it can then be used to correct for distortion in a recording. In Figure the response to a voltage step is given by the exponential curve BCD, and the level which it will finally attain is AD. At any point C, the value CF is less than the full response FE by an amount CE. If the tangent at C be drawn to cut AD, then EG is the subtangent. The value of EG (in sec) is constant at all points of the curve. When EG is known, CE can be determined. A correction can now be applied to an experimental curve (as in Figure ) obtained under the same recording conditions of resistance and capacitance. At any point Q, a vertical line and a tangent are drawn. The point E^ is marked on the vertical where the horizontal line E^G is equal to the subtangent EG. The point E^ represents the true voltage at this time on the response curve. The correction is performed at successive points on the curve. Recording within a mass of active tissue—Records may be required from a structure within a tissue mass, when activity is widespread and varies from point to point. The electrode may have to pass through one active region in order to study another beyond it. It is possible that activity may be recorded by capacitive coupling through the walls of the shank of the electrode (Hodgkin^). The degree of interference will depend on the relative voltages of the source and interfering region, and on the dimensions of the latter. A simple experiment to illustrate this phenomenon can be performed by applying a 10 kc sine wave to a bath of fluid while an electrode is introduced: 555. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration an
Size: 1701px × 1469px
Photo credit: © The Book Worm / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: ., bookcentury1900, bookcollectionameri, bookcollectionbiodiversity
