A system of surgery : theoretical and practical . their roughened state, or by the presence in the blood of some irritating the first of these seems the more likely hypothesis. Slight congestion is alsoobserved in the nearest vascular tissue, ix. the synovial membrane, but not suflS-cient in most cases to do more than produce trifling hypersecretion. This irritationof the synovial membrane was supposed by Cruveilhier, Adams, and Sir B. Brodie tobe the initial change ; but, as stated, there appears to be an earlier degenerative onein the cartilage. As the disease advances, however, a
A system of surgery : theoretical and practical . their roughened state, or by the presence in the blood of some irritating the first of these seems the more likely hypothesis. Slight congestion is alsoobserved in the nearest vascular tissue, ix. the synovial membrane, but not suflS-cient in most cases to do more than produce trifling hypersecretion. This irritationof the synovial membrane was supposed by Cruveilhier, Adams, and Sir B. Brodie tobe the initial change ; but, as stated, there appears to be an earlier degenerative onein the cartilage. As the disease advances, however, and the cartilage becomes moreand more worn away until bone actually plays against bone, the irritation becomesgreater. The cartilage at the borders becomes more lumpy, the irritated bone com-mences to throw out osseous tissue at the periphery of the joint, while worn anderoded by friction at the points of contact. All this is a slow process, and the newosteophytes are made up of a soft spongy tissue, likened by Billroth to tallow drip-pings, whi
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