. Fever, thermotaxis, and calorimetry of malarial fever. Fig. 7. about the same length of time. But, as a fact, the probecauses temperature curves not equal in height or duration,and this I regard as a strong argument in favor of circum-scribed centres. The real question is where do you usuallyobtain the highest temperature, and how wide is this area ?The point at issue is not a mere rise of temperature of small 20 ISAAC OTT. amount and short in duration. The difficulty which erects is that he has a series of small rises, about1050 F., in nearly all his observations upon the first da


. Fever, thermotaxis, and calorimetry of malarial fever. Fig. 7. about the same length of time. But, as a fact, the probecauses temperature curves not equal in height or duration,and this I regard as a strong argument in favor of circum-scribed centres. The real question is where do you usuallyobtain the highest temperature, and how wide is this area ?The point at issue is not a mere rise of temperature of small 20 ISAAC OTT. amount and short in duration. The difficulty which erects is that he has a series of small rises, about1050 F., in nearly all his observations upon the first day andless upon the second day; that there cannot be pointswhere lesions are accompanied by temperatures muchhigher and this point be circumscribed. If a line bedrawn from the most anterior thermotaxic centre to the Tkmp. Exp Fig. 8. most posterior of the basal centres, it will measure abouthalf an inch ; at one end by puncture a temperature attainsits height, in twenty-four to forty-eight hours, of 1070, andlasts about three days. At the other end of the half inch, bypuncture a temperature of 1091/2 0 is attained in three hours,andlasts but a short time,returning to normal in four or five these two points are two other centres which whenpunctured are associated with temperatures of io5°,rapidly reached and continued about three days. Temper-ature is as sensitive to lesion about these thermotaxic basalcentres as arterial tension to irritations of distant parts ; THE THE RMO-POL YPNCEIC CENTRE. 2 I but these changes in arterial pressure do not prove that nochief vaso-motor centre exists. I should like to state herethat whilst a rise of temperature is often attained by insultsto these centres at the base of the brain, it by no meansfollows that it always does ; for I have often seen the


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Keywords: ., booksubjectbodytemperature, booksubjectfever, booksubjectmalaria