. A text-book upon the pathogenic Bacteria and Protozoa for students of medicine and physicians. Bacteriology; Pathogenic bacteria; Protozoa. 694 Tuberculosis Isolation and cultivation of these organisms is easy, and more than any other measure serves to differentiate them from the tubercle bacillus, as they grow upon nearly all the culture-media with rapidity and luxuriance. PSEUDOTUBERCULOSIS Bacillus Pseudotuberculosis Pfeififer,* Malassez and Vignal,t Eberth,t Chantemesse,§ Charrin, and Roger 11 have all reported cases of so-called pseudotuberculosis occurring in guinea-pigs, and character


. A text-book upon the pathogenic Bacteria and Protozoa for students of medicine and physicians. Bacteriology; Pathogenic bacteria; Protozoa. 694 Tuberculosis Isolation and cultivation of these organisms is easy, and more than any other measure serves to differentiate them from the tubercle bacillus, as they grow upon nearly all the culture-media with rapidity and luxuriance. PSEUDOTUBERCULOSIS Bacillus Pseudotuberculosis Pfeififer,* Malassez and Vignal,t Eberth,t Chantemesse,§ Charrin, and Roger 11 have all reported cases of so-called pseudotuberculosis occurring in guinea-pigs, and characterized by the formation of cellular nodules in the liver and kidneys much resembling miliary tubercles. Cultures made from them showed the presence of a small motile bacillus which could easily be stained by ordinary methods. When introduced subcutaneously into guinea-pigs, the original disease was reproduced. Morphology and Cultivation.—Bacillus pseudotuberculosis is characterized by PfeiflEer as follows: The organisms are rod-shaped, the rods varying in length ( to ju) and sometimes united in chains. They may be almost round, and then. Fig. 281.—Bacillus pseudotuberculosis from agar-agar. X 1000 (Itzerott and Niemann.) resemble diplococci. They stain by ordinary methods, but not by Gram's method. They are motile and have flagella like the typhoid and colon bacilli. They form no spores. Upon gelatin and agar-agar, circular colonies with a dark nucleus surrounded by a transparent zone are formed. In gelatin punctures the bacilli grow all along the line of puncture and form a surface growth with concen- tric markings. The gelatin is not Uquefied. The bacilli grow readily upon agar and on potato, but without characteristic appearances. In bouillon a diffuse turbidity occurs, with floating and suspended flakes. Milk is not altered. Pathogenesis.—The bacillus is fatal to mice, guinea-pigs, rabbits, hares, and other rodents in about twenty days after inoculation. At the


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Keywords: ., bookcentury1900, bookdecade1910, booksubjectbacteri, bookyear1916