. Kirkes' handbook of physiology . Fig. 193.—Capillary Network from Human Pia Mater, Showing also an Arteriole in OpticalSection ; and a Small Vein. X 350. A, Vein; B, arteriole; C, large capillary; D, small capillaries.(Bailey.) become rigid from disease, and when the beat of the heart is so slow or sofeeble that the blood at each cardiac systole has time to pass on to the capil-laries before the next stroke occurs; the amount of blood sent at each strokebeing insufficient properly to distend the elastic arteries. It was formerly supposed that the occurrence of any transudation fromthe interi
. Kirkes' handbook of physiology . Fig. 193.—Capillary Network from Human Pia Mater, Showing also an Arteriole in OpticalSection ; and a Small Vein. X 350. A, Vein; B, arteriole; C, large capillary; D, small capillaries.(Bailey.) become rigid from disease, and when the beat of the heart is so slow or sofeeble that the blood at each cardiac systole has time to pass on to the capil-laries before the next stroke occurs; the amount of blood sent at each strokebeing insufficient properly to distend the elastic arteries. It was formerly supposed that the occurrence of any transudation fromthe interior of the capillaries into the midst of the surrounding tissues wasconfined, in the absence of injury, strictly to the fluid part of the blood; in THE CAPILLARY FLOW ^01. other words, that the corpuscles could not escape from the circulating stream,unless the wall of the containing blood-vessel was ruptured. It is true thatthe English physiologist Augustus Waller affirmed in 1846 that he had seenblood-corpuscles, both red and white, pass bodilythrough the wall of the capillary vessel in whichthey were contained (thus confirming what hadbeen stated a short time previously by Addison),and that as no opening could be seen before theirescape, so none could be observed afterward, sorapidly was the part healed. But these observationsdid not attract much notice until the phenomenonof escape of the blood-corpuscles from the capil-laries and minute veins, apart from mechanical injury,was rediscovered by Cohnheim in 1867. Cohnheims experiment demonstrating the pas-sage of the corpuscles through the wall of the blood-vessel is performed in the following manner: A frogis curarized, that is to say paralysis is produced byinjecting under the skin a minute quantity o
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