American practice of surgery : a complete system of the science and art of surgery . hich increase insize and numbers, penetrate the basement membranes, burst through the muscu- 356 AMERICAN PRACTICE OF SURGERY. laris mucosir, anil ovontiuilly appear in the muscular wall. The term adeno-car-ciiiuma, so often eniployed, refers to a carcinoma that reproduces the glandulartype in a recognizable degree. The large majority of carcinomata are adeno-car-cinomata. Having considered the manner in which carcinomata originate, we may prop-erly inquire into their mode of growth. Tliis dejKnds in large mea
American practice of surgery : a complete system of the science and art of surgery . hich increase insize and numbers, penetrate the basement membranes, burst through the muscu- 356 AMERICAN PRACTICE OF SURGERY. laris mucosir, anil ovontiuilly appear in the muscular wall. The term adeno-car-ciiiuma, so often eniployed, refers to a carcinoma that reproduces the glandulartype in a recognizable degree. The large majority of carcinomata are adeno-car-cinomata. Having considered the manner in which carcinomata originate, we may prop-erly inquire into their mode of growth. Tliis dejKnds in large measure on thenature of the supporting stroma of the jiart involved. In the case of connectivetissue we have a meshworkof fibres, between wliich li(^ the cellsproper. The spacesform an interconnnunicating systeni and are the radicles of the lymphatic chan-nels. Now, if a mass of epithelial cells begins to proliferate, and does not extendto the surface after the manner of a typical growth, it extends downward andat once enters this system of tissue spaces, where it continues to FiQ. 111.—Epithelioma. This section shows very well the aberrant downward growth of the super-ficial epithelium of the skin. Winckel No. 3, without ocular. (From the authors collection.) The epithelial-cell clusters invariably lie within the lymph spaces and extendby way of the lymph channels. In hardened sections, in which the epithelialcells have shrunk away from their boundaries, it is often possible to detect alayer of endothelium lining the alveolus, similar to that lining the 15mphatics. In a general way, the cells forming a carcinoma resemble those of the epithelialstructures from which they arise. Close study, however, will reveal some nota-ble differences. The carcinoma cells are often larger and possess larger nuclei;there is considerable variation in shape; and degenerative changes are often to beobserAed in the protoplasm. Single cells of relatively great size, containing a sin-gle large
Size: 1583px × 1578px
Photo credit: © The Reading Room / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: ., bookauthorbuckalbe, bookcentury1900, bookdecade1900, bookyear1906
