The Journal of laboratory and clinical medicine . Fig. 18.—(150350.) Melano-epithelioma originating from a birthmark after slight Fig. 19. — (Same as Fig. 18.) Carcinomatous i)ortion of tlie tumor. ( x350 diam.) Lathrop and Loeb in their non-breeding mice would seem to indicate (in connec-tion with other evidence concerning the physiologic activity of cholesterin) thatthe g-enerative organs utilize a certain proportion of the available ciiolesterin forthe formation of the reproductive cells. SUMM.\RY. 1. Clinical data and experimental observation alike suggest that the causative


The Journal of laboratory and clinical medicine . Fig. 18.—(150350.) Melano-epithelioma originating from a birthmark after slight Fig. 19. — (Same as Fig. 18.) Carcinomatous i)ortion of tlie tumor. ( x350 diam.) Lathrop and Loeb in their non-breeding mice would seem to indicate (in connec-tion with other evidence concerning the physiologic activity of cholesterin) thatthe g-enerative organs utilize a certain proportion of the available ciiolesterin forthe formation of the reproductive cells. SUMM.\RY. 1. Clinical data and experimental observation alike suggest that the causativefactor in the production of malignant proliferation is widely distributed within the organism. 674 The Journal of Laboratory and Clinical Medicine 2. There is reason to believe that this fundamental factor is chemical in its nature. 3. The existence of a gradual transition between normal, reparative, benignand malignant proliferation has been commented on by many observers. 4. The evident connection observed between an increase of cholesterin andproliferation, both normal and abnormal, seems to suggest that cholesterin mayact as a


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Keywords: ., bookcentury1900, bookdecade1910, booksubject, booksubjectmedicine