. The thyroid gland in health and disease. Fig. 33.—Large congenital goitre in premattirely-born goat; experimentally-produced. The animal was quite hairless. (Reproduced by courtesy of the Editor of the Practitioner.) (8) Goitre has been produced experimentally in animals— rats and goats—by feeding them on cultures, from thefaeces of goitrous and non-goitrous subjects, grownunder aerobic and anaerobic conditions : those grownunder anaerobic conditions being the more potent inthis respect. [9, 10, 20.] (9) Congenital goitre (fig. 33), cretinism (fig. 34), and congenital CAUSAL AGENT OR AGENTS


. The thyroid gland in health and disease. Fig. 33.—Large congenital goitre in premattirely-born goat; experimentally-produced. The animal was quite hairless. (Reproduced by courtesy of the Editor of the Practitioner.) (8) Goitre has been produced experimentally in animals— rats and goats—by feeding them on cultures, from thefaeces of goitrous and non-goitrous subjects, grownunder aerobic and anaerobic conditions : those grownunder anaerobic conditions being the more potent inthis respect. [9, 10, 20.] (9) Congenital goitre (fig. 33), cretinism (fig. 34), and congenital CAUSAL AGENT OR AGENTS OF GOITRE 99 parathyroid disease (figs. 65-67), have been producedexperimentally in the offspring of such animals bycontinuing to feed the mothers throughout pregnancywith these cultures. [16, 24, 25.](10) Finally, vaccines prepared from intestinal organisms arecapable of causing the disappearance of recent cases of


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