. A text-book of practical therapeutics, with especial reference to the application of remedial measures to disease and their employment upon a rational basis . ose 5 to 20 minims (), and the extract(Exlractum Sumbul, U. S.), dose 1 to 5 grains (). Thetincture (Tinctura Sumbul, dose 1 to 4 drachms () is officialin the B. P. Goodell used the following formula: R—Extract sumbul gr. xx (). Ferri sulph gr. xx (). Asafceditse gr. x (). Acid, arsenosi gr J ().—M. Ft. in pil. No. xx. S.—One t. i. d. after meal. To be of any value the drug must be fresh, and car
. A text-book of practical therapeutics, with especial reference to the application of remedial measures to disease and their employment upon a rational basis . ose 5 to 20 minims (), and the extract(Exlractum Sumbul, U. S.), dose 1 to 5 grains (). Thetincture (Tinctura Sumbul, dose 1 to 4 drachms () is officialin the B. P. Goodell used the following formula: R—Extract sumbul gr. xx (). Ferri sulph gr. xx (). Asafceditse gr. x (). Acid, arsenosi gr J ().—M. Ft. in pil. No. xx. S.—One t. i. d. after meal. To be of any value the drug must be fresh, and care must be takenthat the crude drug from which it is made is a good sample. SUPRARENAL GLAND AND ADRENALIN. 435 SUPRARENAL GLAND AND ADRENALIN. The suprarenal gland, or its active principle, has become withinthe last few years one of our most valued remedies. Its chief use inmedicine depends upon its extraordinary power of producing contrac-tion of small bloodvessels and capillaries with which it is brought incontact. It also exercises a marked constricting effect on the blood-vessels of the general arterial system when given intravenously. Fig. TX ^mmm^ Showing the rise of arterial pressure produced by the injection of of adrenalin into the vein of a dog. The medullary portion of the glands is chiefly concerned with theelaboration of the active physiological principle, which has beenisolated by a Japanese chemist, Takamine, and called occurs in tiny, almost microscopic, white crystals of variousforms, which are soluble in water after slight acidulation with hydro-chloric acid. Physiological Action.—When locally applied to mucous membranesextract of this gland, or adrenalin, produces great blanching by reasonof its powerful constriction of the capillaries of the part. So greatis this constriction that the superficial tissues are practically blood-less while its influence lasts. This local effect is due to stimulationof the muscular fibres
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