. A practical treatise on diseases of the skin, for the use of students and practitioners. 690 DISEASES OF THE SKIN. become the seat of an oedema, accompanied by pruritus and other sub-jective sensations. Later, brownish, bluish-red, or dark purplishspots appear, out of which develop pin-head- to pea-sized nodules,gradually increasing in volume, discrete, tender, and often may be the seat of lancinating and radiating pains. As theymultiply, a lardaceous infiltration progressively involves the depth ofthe integument, until an elephantiasic condition is produced, a hand,a foot, or a


. A practical treatise on diseases of the skin, for the use of students and practitioners. 690 DISEASES OF THE SKIN. become the seat of an oedema, accompanied by pruritus and other sub-jective sensations. Later, brownish, bluish-red, or dark purplishspots appear, out of which develop pin-head- to pea-sized nodules,gradually increasing in volume, discrete, tender, and often may be the seat of lancinating and radiating pains. As theymultiply, a lardaceous infiltration progressively involves the depth ofthe integument, until an elephantiasic condition is produced, a hand,a foot, or an entire limb becoming of cartilaginous hardness, bluishin tint, and covered with a smooth, mammillated, squamous, or rugousenvelope, which may be also the site of tumors of considerable tumors are fewer in number and smaller in volume as theyspread from the distal to the proximal parts of the limb. They maybe sessile, pedunculated, and grouped, but they are always of a deepbluish or violaceous tint. These growths may remain for a long time stationary, or they maybe entirely


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Keywords: ., bookauthorhydejamesnevins184019, bookcentury1800, bookdecade1890