. Fever, thermotaxis, and calorimetry of malarial fever. er injury of caudate nucleus, and after lesionof the cruciate cortex centre above it, are totally for the same reason can the temperature variations,by insults to centres behind or beneath it, be ascribed tothe caudate nucleus. It makes a great difference whetheryou select the point where a lesion with probe is accom-panied by the highest temperature,or to a point in the neigh- THE THERMO-POL YPNQLIC CENTRE. I 9 borhood where you have temperatures lower and notlasting as long as those made nearer the thermotaxic cen-tre


. Fever, thermotaxis, and calorimetry of malarial fever. er injury of caudate nucleus, and after lesionof the cruciate cortex centre above it, are totally for the same reason can the temperature variations,by insults to centres behind or beneath it, be ascribed tothe caudate nucleus. It makes a great difference whetheryou select the point where a lesion with probe is accom-panied by the highest temperature,or to a point in the neigh- THE THERMO-POL YPNQLIC CENTRE. I 9 borhood where you have temperatures lower and notlasting as long as those made nearer the thermotaxic cen-tre. All opinion is that the sensory fibres stand in a veryclose relation with these thermotaxic centres, in order toregulate the relation between H. P. and H. D. The rela-tion of the sensory nerves to the polypnoeic centre, whichis a regulator of heat, also confirms this view. If these centres were not circumscribed, then usually aprobe should cause about the same rise of temperature allover the base of the brain, and this rise should continue ~Exp. Fig. 7. about the same length of time. But, as a fact, the probecauses temperature curves not equal in height or duration,and this I regard as a strong argument in favor of circum-scribed centres. The real question is where do you usuallyobtain the highest temperature, and how wide is this area ?The point at issue is not a mere rise of temperature of small 20 ISAAC OTT. amount and short in duration. The difficulty which erects is that he has a series of small rises, about1050 F., in nearly all his observations upon the first day andless upon the second day; that there cannot be pointswhere lesions are accompanied by temperatures muchhigher and this point be circumscribed. If a line bedrawn from the most anterior thermotaxic centre to the Tkmp. Exp 237.


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Keywords: ., booksubjectbodytemperature, booksubjectfever, booksubjectmalaria