. Manual of bacteriology. Bacteriology. DISTRIBUTION OF THE BACILLI. 439 oxgyen; in strictly anaerobic conditions almost no growth takes place. The organism in its powers of resistance corresponds with other spore-free bacilli, and is readily killed by heat, an exposure for an hour at 58° C. being fatal. On the other hand, it has remarkable powers of resistance against cold ; it has been ex- posed to a temperature several degrees below freezing-point without being killed. Experiments on the effects of drying have given somewhat diverse results, but as a rule the organism has been found to be d


. Manual of bacteriology. Bacteriology. DISTRIBUTION OF THE BACILLI. 439 oxgyen; in strictly anaerobic conditions almost no growth takes place. The organism in its powers of resistance corresponds with other spore-free bacilli, and is readily killed by heat, an exposure for an hour at 58° C. being fatal. On the other hand, it has remarkable powers of resistance against cold ; it has been ex- posed to a temperature several degrees below freezing-point without being killed. Experiments on the effects of drying have given somewhat diverse results, but as a rule the organism has been found to be dead after being dried for from six to eight days, though sometimes it has survived the process for a longer period; exposure to direct sunlight for three or four hours kills it. When cultivated out- side the body the organism often loses its virulence, but some races re- main virulent in culture for a long period of time. Anatomical Changes and Distribution of Bacilli. — The disease occurs in several forms, the biL- bonic and the pithiioiiary be- ing the best recognised ; to these may be added the scpticcEmic. The most striking feature in the bubonic form is the affection of the lymphatic glands, which undergo intense inflammatory swell- ing, attended with haemorrhage, and generally ending in a greater or less degree of necrotic softening if the patient lives long enough. The connective tissue around the glands is similarly affected. The bubo is thus usually formed by a col-. FiG. 151. — Section of a human lymphatic gland in plague, showing the injection of the lymph paths and sinuses with masses of plague bacilli — seen as black areas. Stained with carbol-lhionin-blue. X Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Muir, Robert, 1864-; Ritchie, James, 1864-1923; Harris, Norman MacLeod. New Yo


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