Organic and functional nervous diseases; a text-book of neurology . referable to the spinalcord have been observed. We may therefore say that both in acuteand chronic anaemia of the spinal cord it is impossible to make adiagnosis of the condition; we can only suspect their presence. PERNICIOUS :MIA AND ITS EFFECTS ON THE SPINAL CORD. There are some very marked changes produced in the nervous sys-tem by a state of pernicious anaemia,^ and although these changes whenthey are slight may not produce symptoms, it is as a rule possible todetect in these cases evidence of disease of the spinal co
Organic and functional nervous diseases; a text-book of neurology . referable to the spinalcord have been observed. We may therefore say that both in acuteand chronic anaemia of the spinal cord it is impossible to make adiagnosis of the condition; we can only suspect their presence. PERNICIOUS :MIA AND ITS EFFECTS ON THE SPINAL CORD. There are some very marked changes produced in the nervous sys-tem by a state of pernicious anaemia,^ and although these changes whenthey are slight may not produce symptoms, it is as a rule possible todetect in these cases evidence of disease of the spinal cord. Pathology. — A diffuse sclerosis has been found in all the casesreported. This is not limited to any one system of fibres, but involves ^ Frank Billings, The Shattuck Lecture, 1902. Putnam and Taylor, Journal ofNervous and Mental Disease, 1901, vol. xxviii, pp. 1 and 74. 392 PERNICIOUS AN.^MIA OF SPINAL CORD. 393 any or all of the white columns. As a rule it is more intense in theposterior golumns, and more marked in the cervical and upper dorsal Fig. Diffuse sclerosis of the cervical region in pernicious ansemia. (Billings.) segments of the cord than elsewhere; but the lateral and anteriorcolumns do not escape, and the entire length of the cord may be 174 to 176 demonstrate the lesion in cases reported by Billings. Fig. 175.
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