. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . fragmentary walls of the chorion are very fibrousand the growth of the syncytium is very irregular. Undoubt-edly the ovum collapsed some days before the uterus wasscraped. The whole specimen is buried more or less in aslimy mass rich in leucocytes, which indicates that the uterinetissue was markedly inflamed. No. 396. Ovum, about 7 mm. in diameter, with the coelom measuring3x2 mm. Tubal pregnancy. Dr. Castler, Baltimore. The tube was removed April 24, 1907, from
. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . fragmentary walls of the chorion are very fibrousand the growth of the syncytium is very irregular. Undoubt-edly the ovum collapsed some days before the uterus wasscraped. The whole specimen is buried more or less in aslimy mass rich in leucocytes, which indicates that the uterinetissue was markedly inflamed. No. 396. Ovum, about 7 mm. in diameter, with the coelom measuring3x2 mm. Tubal pregnancy. Dr. Castler, Baltimore. The tube was removed April 24, 1907, from a womantwenty-one years old. Last period, March 5, followed by abrownish discharge on April 11. Diagnosis of tubal preg-nancy on April 23. The abdominal cavity was found wellfilled with blood and the tube was still bleeding through theinternal ostium. The whole tube was removed and placed ina 10 per cent solution of formalin. No. i.] ORIGIN OF HUMAN MONSTERS. 357 The hardened tube is 40 mm. in length and 20 mm. indiameter. It was cut into blocks 5 mm. thick and imbeddedin colloidin. Two of the blocks were found to contain the. Fig. 396.—Section of the chorion containing the embryonic mass. X 35times. E, remnant of the embryo; UV, umbilical vesicle. ovum and these were cut out and reimbedded in paraffin andcut into serial sections. The sections show that the ovumhas unusually long villi, fully 5 mm. long, which ramify 358 MALL. [Vol. XIX. throughout the blood in the tube and in many instances areattached to the decidua. The syncytium is well walls of the tube are markedly distended, infiltrated withred corpuscles and leucocytes, many contain fragmented nuclei,which are also scattered throughout the decidua. Within the coelom of the chorion there is a double vesicle,the large one, 2x1 mm. in diameter, showing all the char-acteristics of the umbilical vesicle. Its layer of mesodermappears to be thickened and at numerous points it has becomeadherent to the inner wa
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