. Bacterial pyrogens; particularly pyrogenic polysaccharides of bacterial origin : an annotated bibliography. Pyrogens. l6l -19^6- TUCKER, J. Typhoid shock therapy- Cleveland Clin. Quart. 13:67-72^ 19^6 Experiences with fever elicited by typhoid vaccine in several thousand patients during the past 15 years have been useful for deterrainlng correct applications and contraindications for typhoid shock therapy. Most successful results have been rea- lized in the following conditions: central nervous system virus Infections, chronic rheumatoid arthritis, chorea,and eye and skin diseases. WARREN, M


. Bacterial pyrogens; particularly pyrogenic polysaccharides of bacterial origin : an annotated bibliography. Pyrogens. l6l -19^6- TUCKER, J. Typhoid shock therapy- Cleveland Clin. Quart. 13:67-72^ 19^6 Experiences with fever elicited by typhoid vaccine in several thousand patients during the past 15 years have been useful for deterrainlng correct applications and contraindications for typhoid shock therapy. Most successful results have been rea- lized in the following conditions: central nervous system virus Infections, chronic rheumatoid arthritis, chorea,and eye and skin diseases. WARREN, M. R. and WERNER, H, W, The evaluation of antipyretics against pyrogen-induced fever J. Am. Pharm. A. 35:257-259^ 19^6 A purified pyrogen was prepared from Proteus vulgaris by cellular lysis, repeated phenol extraction, dialysis and acetone precipi- tation. The minimal pyrogenic dose was cc• per kg. body weight in the rabbit when the pyrogen was injected subcutaneously. Temperature was reduced to normal levels by the oral administra- tion of amlnopyrene, acetanilid or acetylsalicylic acid; aceto- phenetidln arrested temperature Increase but did not reduce fever. WEENS, H. S. and HEYMAN, A, Cardiac enlargement in fever therapy Induced by intravenous in- jection of typhoid vaccine Arch. Int. Med, 77:307-316, 19^^6 Enlargement of the heart during typhoid vaccine therapy was noted In 8 of 15 patients with neurosyphilis. In four other patients, cardiac changes persisted for six months following hyperpyrexia. No sigrllflcant differences could be found between patients with normal cardiac size and those with enlarged structures. Blood volume, cardiac output, and protein and hemoglobin levels did not differ widely from the norm. WESTPALL, B. B. and DUNN, T. E, Blood uric acid and proteose, body temperature and glomerular clearance of rabbits Implanted with the Brown-Pearce carcinoma and treated with the polysaccharide from Serratia marcescens J. Nat. Cancer Inst. 7:115-121, 19^6.


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