. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . e pedicle. At one point thethickening is greatly increased and immediately below it thereare two small vesicles lined with epithelial cells. The maincavity of the vesicle is lined with a layer of cubical cells, andis filled with a considerable quantity of round cells. Thiscavity is hour-glass shaped and extends to the walls of thechorion, as the figures show. The mesoderm of the vesicle 172 MALL. [Vol. XIX. is increased in quantity and is filled with wandering c
. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . e pedicle. At one point thethickening is greatly increased and immediately below it thereare two small vesicles lined with epithelial cells. The maincavity of the vesicle is lined with a layer of cubical cells, andis filled with a considerable quantity of round cells. Thiscavity is hour-glass shaped and extends to the walls of thechorion, as the figures show. The mesoderm of the vesicle 172 MALL. [Vol. XIX. is increased in quantity and is filled with wandering cells. Atthe base of the vesicle there are several blood spaces filledwith blood. No. 79. Ovum, 50 x 50 x 50 mm.; embryo, C. R., 32 mm. Dr. Briggs, Blackville, S. C. Dr. Briggs writes that the abortion took place 91 days afterthe beginning of the last menstrual period. The specimen came into my hands well hardened in strongalcohol with all of the membranes intact. When opened itwas found that the inner walls of the-amnion and the embryowere entirely covered with a layer of firmly coagulated gran-ular substance or granular Fig. 79.—Photograph of ovum cut open, showing the embryo encrustedin granular magma. Natural size. The chorion is very hemorrhagic and thick on one side,while on the other it is very thin. The sections show appar-ently normal structures in the thick, portion, while in the thinportion there is an extensive leucocytic infiltration. At thislatter point the walls of the chorion are markedly changed,being invaded by the syncytium as well as by leucocytes. Serial sections of the embryo show that it must have beenstrangulated before the abortion took place. The central No. i.] ORIGIN OF HUMAN MONSTERS. 173 nervous system is greatly macerated, the liver has disinte-grated and the aorta is greatly distended. The rest of theembryo appears normal. The intestine is almost entirelywithin the peritoneal cavity; a single loop of it still remains inthe opening commun
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