Illustration of paralysis due to polio. From "Observations on states of paralysis of the lower extremities and their treatment," by Jacob von Heine, 1840. The first clinical description of polio was by the English physician Michael Underwood in 1789, where he refers to polio as "a debility of the lower extremities." The work of physicians Jacob Heine in 1840 and Karl Oskar Medin in 1890 led to it being known as Heine-Medin disease. The disease was later called infantile paralysis, based on its propensity to affect children. Colorized.

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