. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . Elsewhere it is smooth. The amnionis filled with a granular mass, which was swept out easilywhen opened. Between the amnion and chorion there is anirregular mass of mothers blood, which is partly organized,showing that the chorion had ruptured some time before theabortion took place. The tissues of the villi and the chorionare somewhat fibrous, with very few degenerated blood-ves- No. I.] ORIGIN OF HUMAN MONSTERS. 235 sels within them, indicating that the circul
. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . Elsewhere it is smooth. The amnionis filled with a granular mass, which was swept out easilywhen opened. Between the amnion and chorion there is anirregular mass of mothers blood, which is partly organized,showing that the chorion had ruptured some time before theabortion took place. The tissues of the villi and the chorionare somewhat fibrous, with very few degenerated blood-ves- No. I.] ORIGIN OF HUMAN MONSTERS. 235 sels within them, indicating that the circulation had ceasedsome time before the abortion, which is confirmed by a studyof the embryo. The external form of the embryo indicates that it wasnearly 50 days old when it died, for, with the exception ofthe head, its form is practically normal. The menstrual his-tory makes it 87 days, and if 28 is subtracted, ten days arestill left, which is time enough in which to bring on theinternal changes found within it. In general the organs are sharply defined, but they do notstain well; the cells appear as in coagulation necrosis. The. Fig. 226a.—Photograph of the embryo. Enlarged 2 diameters. cartilages are also well formed, and the maxilla, mandible,clavicle, humerus, ulna, radius, femur and tibia have begunto ossify. All this indicates that this embryo died quitesuddenly and that the changes within it are to be viewed aspost-mortem changes. The vascular system is well developed, the heart musclebeing normal in shape but very fibrillar; it does not stainwell. Most of the large vessels are empty and the bloodcells are scattered throughout the tissues of the embryo andthe cord. The muscle fibers are unusually well marked, andthe connective tissue seems to be thickened. 236 MALL. [Vol. XIX. The most marked changes are seen in the head. Much ofthe epidermis is still in place, but some of it has fallen the back of the head the destructive process has includedthe back of the brain
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