. Ciba Foundation colloquia on ageing. Old age; Aging; Animals -- growth & development. Biological Approach in Study of Ageing 7 since in each case the large variance is an expression of poor homeostasis, and this in turn may represent a partial with- drawal of natural selection. The variance of single characters has been used as a measure of inbreeding depression (Maclaren and Michie, 1954, 1955) and it might in some instances be convenient to use 5000. 0 10 20 30 40 50 50 70 AGE AT DEATH (Yr.) Fig. 1. Distribution by age of deaths from all causes (white males, 1939-41) and of pedest
. Ciba Foundation colloquia on ageing. Old age; Aging; Animals -- growth & development. Biological Approach in Study of Ageing 7 since in each case the large variance is an expression of poor homeostasis, and this in turn may represent a partial with- drawal of natural selection. The variance of single characters has been used as a measure of inbreeding depression (Maclaren and Michie, 1954, 1955) and it might in some instances be convenient to use 5000. 0 10 20 30 40 50 50 70 AGE AT DEATH (Yr.) Fig. 1. Distribution by age of deaths from all causes (white males, 1939-41) and of pedestrian deaths in road accidents (England and Wales, 1950). (Reproduced, with permission, from Comfort, 1956. Lancet, ii, 773.) some such measure of the variance of a number of characters in estimating senescence. As in inbred strains, however, the characters whose variance increases with age are quite irreg- ularly distributed between species and between genetic races of the same species. By measuring the probability of death from the sum total of causes we are using a measure applicable to all organisms, which can be treated mathematically by con- venient methods, and which is experimentally consistent— often to a very high degree. In man and in some inbred lines. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Ciba Foundation; Wolstenholme, G. E. W. (Gordon Ethelbert Ward). Boston, Little, Brown
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