. Adventures in radioisotope research;. Radioactive tracers; Radiobiology. Brain Tolal tissue »; Broin Total fats mm. Fig. 4. Effect of dinitro-cyclo-pentylphenol on the incorporation of i*C into total fats (b) and total tissue (a) of the brain of the mouse, i^C injected as CHg^COONa. formation rate of fats and other labelled components, but also of an en- hanced dilution of the labelled acetate or its transportation products by endogenous inactive compounds. Assuming the half-life time of the average fatty acid molecule in the mouse to bel8 days, the metabolism of 1 gm fatty acids presen
. Adventures in radioisotope research;. Radioactive tracers; Radiobiology. Brain Tolal tissue »; Broin Total fats mm. Fig. 4. Effect of dinitro-cyclo-pentylphenol on the incorporation of i*C into total fats (b) and total tissue (a) of the brain of the mouse, i^C injected as CHg^COONa. formation rate of fats and other labelled components, but also of an en- hanced dilution of the labelled acetate or its transportation products by endogenous inactive compounds. Assuming the half-life time of the average fatty acid molecule in the mouse to bel8 days, the metabolism of 1 gm fatty acids present in the muscles of a 20 gm mouse will lead to the formation of about 1 millimol en- dogenous (at the start inactive, later slightly active) acetic acid. In this calculation only the carcass fatty acids are considered (4). Tf under the eff(H't of the the carcass fatty acids should be catabolized at an enhanced rate, for example, twice as rapidly as in the controls (inac- tivation of pyruvate is leading to the accumulation of acetate as well), the dilution of the active muscle acetate and its transformation products. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Hevesy, Georg von, 1885-1966. New York, Pergamon Press
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