AMAarchives of neurology & psychiatry . sis from those in other diseases. Death in generalparesis seldom occurs without some complicating terminal infection 2. Xissl: Zur Histopathologic der paralytischen Rinderkrankung. Xisslhistologische und histopathologische Arbeiten 1:315. 1904. 3. Alzheimer: Histologische Studien zur Differentialdiagnose der progres-siven Paralyse, Xissl histologische und histopathologische Arbeiten 1:18, 1904. 4. Wernicke : Grundriss der Psychiatric. Ed. 2. Leipzig, Thicme, 1906. 5. Kraepelin: Lehrbuch der Psychiatric, Leipzig. Barth, 1910. 6. Bleuler: Lehrbuch der Psyc


AMAarchives of neurology & psychiatry . sis from those in other diseases. Death in generalparesis seldom occurs without some complicating terminal infection 2. Xissl: Zur Histopathologic der paralytischen Rinderkrankung. Xisslhistologische und histopathologische Arbeiten 1:315. 1904. 3. Alzheimer: Histologische Studien zur Differentialdiagnose der progres-siven Paralyse, Xissl histologische und histopathologische Arbeiten 1:18, 1904. 4. Wernicke : Grundriss der Psychiatric. Ed. 2. Leipzig, Thicme, 1906. 5. Kraepelin: Lehrbuch der Psychiatric, Leipzig. Barth, 1910. 6. Bleuler: Lehrbuch der Psychiatric, Ed. 2. Berlin, Springer, 1918. 346 ARCHiniS OP XEUROLOCV .L\D PSYCHIATRY such as pneumonia, decubitis, etc. More than one half of the patientsof this series died of acute terminal infections. This would seem tointerfere with any possible conclusions concerning the cellular reactionin treated and untreated patients, especially with regard to the presenceof fat in the cells of the cortex. For this reason, as well as for the fact. , ? » -i i. ^^ \» • ; o ; A -; V h^ \ >. ? >• :P •«J. - >. • » .ik. > ? ^ w » * .. ? i ?* ; 4 • i-» «• ^V ». a % ;, \ ? it • !^ . •t^ «? , \ « ? \- , ^ -? . • - ,1 Fig. 4—From same case as Fig. 3. Temporal lobe. Xote characteristicsheath infiltration of capillaries and arterioles. that it is quite difficult to estimate the extent or degree of cell loss ofone case in comparison to another, no conclusions concerning cellchanges are attempted. Bielschowskys stain for nerve fibrils shows nospecific changes of significance. This has also been shown bySpielmeyer. SOLOMOX-T AFT—AXTI SYPHILITIC THERAPY 347 The neuroglia is apparently always increased in general , of course, is a general statement. In the cases of this series therewas some increase in the marginal glia fibers with the usual focalincrease of astrocytes in the outer cortical layer, and frequently longfibers extended from the margin


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