. Animal parasites and human disease. Medical parasitology; Insects as carriers of disease. LOA WORM 309 tissue in and about the eyes, but may also be found creeping under the skin of fingers, breast, back, etc. A loa is said to travel at the rate of about an inch in two minutes, and to become especially active in the presence of direct warmth on the skin, as before a fire. The migration of the worms causes itching and a " creeping " sensation, and in some unexplained way gives rise to temporary swelhngs, from half an inch to four inches in diame- ter, known locally as " Calabar
. Animal parasites and human disease. Medical parasitology; Insects as carriers of disease. LOA WORM 309 tissue in and about the eyes, but may also be found creeping under the skin of fingers, breast, back, etc. A loa is said to travel at the rate of about an inch in two minutes, and to become especially active in the presence of direct warmth on the skin, as before a fire. The migration of the worms causes itching and a " creeping " sensation, and in some unexplained way gives rise to temporary swelhngs, from half an inch to four inches in diame- ter, known locally as " Calabar ; These swelhngs may shift their position an inch or more a day, and may disap- pear to reappear somewhere else. This relation of Loa to Cala- bar swellings has not been definitely proved but there is strong evidence for it. In one case Manson succeeded in finding great numbers of microfilariae of Loa in lymph taken from one of these swellings, a fact which gives color to Manson's hypothe- sis that the swellings might be due to the emission of larvae from the parent worm into the connective tissue. The larvae of the parasite (Fig. 124C), very closely resembling the microfilariae of F. bancrofti, occur in the blood in great numbers, but they have a periodicity di-. A B rectly opposite to that of the latter species in that they swarm in the peripheral blood in the daytime and withdraw to the larger vessels at night. The living larvae of the two species cannot readily be dis- tinguished from each other in fresh blood, u 4- â J â J ^ + â rl ^^"^^ ^^^' Comparison of killed and stained speci- but m dried and stained ^^^^ ^f Microfilaria bancrofti and mf. loa. A, mf. preparations the dead 6ancro/(i, ânote graceful curves; B,m/.ioa, ânote ⢠1 1 irregular scrawl-like curves; C, tails of m/. loa; D, organisms can easily be ^aUs of mf. bancrofti. (After Manson.) identified. The micro- filarice bancrofti are found lying in smooth graceful curves (Fig. 129A), wh
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