. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. DIFFERENTIAL NUTRIENT REQUIRKM 127 time of explanation, whereas the central nervous system continues its development and shows little if any harmful effect of the fluoride. At lower fluoride concentra- tions ( X 10~3 and \Q~3M) there is progressively less effect upon heart-formation. The typical picture of the differential effect is that of an apparently normal embryo with a mass of dispersed and degenerating mesodermal cells occupying the position in which the heart would have formed. The degenerative effect of flu
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. DIFFERENTIAL NUTRIENT REQUIRKM 127 time of explanation, whereas the central nervous system continues its development and shows little if any harmful effect of the fluoride. At lower fluoride concentra- tions ( X 10~3 and \Q~3M) there is progressively less effect upon heart-formation. The typical picture of the differential effect is that of an apparently normal embryo with a mass of dispersed and degenerating mesodermal cells occupying the position in which the heart would have formed. The degenerative effect of fluoride is not limited to heart mesoderm but involves, to some extent, the somite and lateral plate mesoderm. In a number of cases, posterior development of the neural tube is indirectly inhibited, presumably by the absence of inducing mesoderm. Some of these effects are illustrated in Figure 1. Interpretation of the differential effects of fluoride, in terms of interference with the metabolic mechanisms underlying heart as compared with brain-formation, is largely dependent upon knowledge of its site of ; The fact that complete inhibition of development by 10~'JM fluoride can be prevented by substitution of a. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Marine Biological Laboratory (Woods Hole, Mass. ); Marine Biological Laboratory (Woods Hole, Mass. ). Annual report 1907/08-1952; Lillie, Frank Rattray, 1870-1947; Moore, Carl Richard, 1892-; Redfield, Alfred Clarence, 1890-1983. Woods Hole, Mass. : Marine Biological Laboratory
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Keywords: ., bookauthorlilliefrankrat, booksubjectbiology, booksubjectzoology
