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Human physiology . xperiments. He con-cluded from his observations that persistentdosage with pituitary extract retards the growth of the body ingeneral, as shown most deleteriously for the skeletal system, wherethe activity of the connecting cartilages (delay in lengthening oflong bones) is conspicuously diminished, while the activity of theperiosteal ostogenic function (increased development of depth ofepiphyses and diaphyses) is, on the contrary, augmented. Controlanimals treated with extracts of other organs (thyroid, muscle) didnot exhibit similar changes. The results of these new experim
Human physiology . xperiments. He con-cluded from his observations that persistentdosage with pituitary extract retards the growth of the body ingeneral, as shown most deleteriously for the skeletal system, wherethe activity of the connecting cartilages (delay in lengthening oflong bones) is conspicuously diminished, while the activity of theperiosteal ostogenic function (increased development of depth ofepiphyses and diaphyses) is, on the contrary, augmented. Controlanimals treated with extracts of other organs (thyroid, muscle) didnot exhibit similar changes. The results of these new experiments indicate that the hypo-physis is a gland of internal secretion, serving in some way toexcite or regulate the metabolism of the body and the developmentof its various organs, particularly of the skeletal system. Whiletoo indefinite to represent an exact theory of the function of thehypophysis, this view is, on the other hand, supported by clinicalobservations on acromegaly and gigantism, which are often, if not. INTERNAL PEOTECTIVE SECRETIONS 43 always, accompanied by hypertrophy and hyperplasia of thepituitary body. XII. The Suprarenal Capsules or Adrenals are two epithelialflattened bodies of a yellowish-brown colour, situated above the
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Keywords: ., bookcentury1900, bookdecade1910, booksubjectphysiology, bookyear1